University of California, Riverside

Department of Nematology

Isgouhi Kaloshian Faculty Page

Dr. Isgouhi Kaloshian Isgouhi Kaloshian

Professor of Nematology
2107A Genomics Building

Office phone: (951) 827-3913
Fax: (951) 827-3719

Research Areas

Understanding how aphids and nematodes successfully colonize and reproduce on their host plants is the long-term goal of my research program. This knowledge will lead to development of improved resistance in crops to these pests. To dissect these plant-pest interactions, we study root-knot nematode and aphid interactions with their tomato host. This crop provides a unique opportunity to study these interactions as it contains resistant and susceptible tomato lines to these pests. Moreover, resistance to both pests is mediated by the same disease resistance gene, Mi-1, that encodes a nucleotide binding leucine-rich repeat protein. We study the Mi-1-mediated resistance signal transduction pathway to both pests. To understand the mechanism of Mi-1-mediated defense, we investigate gene expression changes in the aphid and the plant host during aphid feeding. Moreover, we study aphid salivary proteins to identify effectors that are recognized by the plant host and those that interfere with the host cellular processes.


Selected Publications

Atamian, H., R. Chaudhary, V. Dal Cin, E. Bao, T. Girke, and I. Kaloshian. 2013. In planta expression or delivery of potato aphid Macrosiphum euphorbiae effectors Me10 and Me23 negatively affect aphid fecundity. Mol. Plant-Microbe Interact. 26:67-74.

Cortada, L., S. Mantelin, S. Verdejo-Lucas, I. Kaloshian. 2012. Marker analysis for detection of the Mi-1.2 resistance gene in tomato hybrid rootstocks and cultivars. Nematology 14:631-642.

Atamian, H., P. A. Roberts, and I. Kaloshian. 2012. High and low throughput screens with root-knot nematodes Meloidogyne spp. J. Vis. Exp. 61, e3629.

Atamian, H.S. and I. Kaloshian. 2012. Construction of RNA-Seq libraries for the Illumina sequencing platform. In: RNA Abundance Analysis: Methods and Protocols. H. Jin and W. Gassmann, Eds. Humana Press, New York, USA.

Atamian, H. S., T. Eulgum, and I. Kaloshian. 2012. SlWRKY70 is required for Mi-1-mediated resistance to aphids and nematodes in tomato. Planta 235:299-309.

Bao, E., T. Jiang, I. Kaloshian, and T. Girke. 2011. SEED: efficient clustering of next-generation sequences. Bioinformatics 27:2502-2509.

Mantelin, S., H.-C. Peng, B. Li, H. S. Atamian, F. L.W. Takken, and I. Kaloshian. 2011. The receptor-like kinase SlSERK1 is required for Mi-1-mediated resistance to potato aphids in tomato. Plant J. 67:459-471.

Kaloshian, I., O. Desmond, and H.S. Atamian. 2011. Disease resistance genes and defense responses during incompatible interactions. In: Genomics and Molecular Genetics of Plant-Nematode Interactions. J. Jones, G. Gheysen and C. Fenoll, eds. Springer, Dordrchet Heidelberg London New York.

Seifi, A., I. Kaloshian, J. Vossen, D. Che, K. K. Bhattarai, J. Fan, Z. Naher, A. Goverse, F. Tjallingii, P. Lindhout, R. Visser, and Y. Bai. 2011. Linked, if not the same, Mi homologue(s) confer(s) resistance to tomato powdery mildew and root-knot nematodes. Mol. Plant-Microbe Interact. 24:441-450.

Bhattarai, K. K., H. S. Atamian, I. Kaloshian*, and T. Eulgem*. 2010. WRKY72-type transcription factors contribute to basal immunity in tomato and Arabidopsis as well as gene-for-gene resistance mediated by the tomato R-gene Mi-1. Plant J. 63:229-240 (* co-corresponding authors).

Gerardo, N.N., B. Altincicek, C. Anselme, H. Atamian, 22 additional authors. 2010. Immunity and other defenses in pea aphids, Acyrthosiphon pisum. Genome Biol. 11:R21.

International Aphid Genomics Consortium. 2010. Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology. Vol. 8: e1000313.

Mantelin, S., K. K. Bhattarai, and I. Kaloshian. 2009. Ethylene contributes to potato aphid susceptibility in a compatible tomato host. New Phytol. 183:444-456.

Bhattarai, K. K., Q-G. Xie, S. Mantlein, U. Bishnoi, T. Girke, D. A. Navarre, and I. Kaloshian. 2008. Tomato susceptibility to root-knot nematodes requires an intact JA signaling pathway. Mol. Plant-Microbe Interact. 21:1205-1214.

Bhattarai, K. K., Q. Li, Y. Liu, S. P. Dinesh-Kumar, and I. Kaloshian. 2007. The Mi-1-mediated pest resistance requires Hsp90 and Sgt1. Plant Physiol. 144:312-323

Bhattarai, K., Q.-G. Xie, D. Pourshalimi,T. Younglove, and I. Kaloshian. 2007. LeCoi1-regulated JA-dependent signaling pathway is not required for the Mi-1-mediated potato aphid resistance. Mol. Plant-Microbe Interact. 20:276-282.

Jablonska, B., J. S. S. Ammiraju, K. Bhattarai, O. Martinez de Ilarduya, S. Mantelin, P. A. Roberts, and I. Kaloshian. 2007. The Mi-9 gene from Solanum arcanum conferring heat-stable resistance to root-knot nematodes is a homologue of Mi-1. Plant Physiol. 143: 1044-1054.

Li,Q., Q.-G. Xie, J. Smith-Becker, D. A. Navarre, and I. Kaloshian. 2006. Mi-1-mediated aphid resistance involves salicylic acid and mitogen-activated protein kinase signaling cascades. Mol. Plant-Microbe Interact. 19:655-664.

Kaloshian, I. and L. L. Walling. 2005. Hemipterans as Plant Pathogens. Annu. Rev. Phytopathol. 43:491-521.

Kaloshian, I. 2004. Gene-for-gene disease resistance: bridging insect pest and pathogen defense. J. Chem. Ecol. 30:2421-2440.

Martinez de Ilarduya, O., G. Nombela, C.-F. Hwang, V. M. Williamson, M. Muñiz and I. Kaloshian. 2004. Rme1 is necessary for Mi-1-mediated resistance and acts early in the resistance pathway. Mol. Plant-Microbe Interact. 17:55-61.

Martinez de Ilarduya, O., Q.-G. Xie, and I. Kaloshian. 2003. Aphid-induced defense responses in Mi-1-mediated compatible and incompatible tomato interactions. Mol. Plant-Microbe Interact. 16:699-708 (Featured on the cover of this issue).

Ammiraju, J.S.S., J.C. Veremis, X. Huang, P.A. Roberts, and I. Kaloshian. 2003. The heat-stable root-knot nematode resistance gene Mi-9 from Lycopersicon peruvianum is localized on the short arm of chromosome6. Theor. Appl. Genet. 106:478-484.

Martinez de Ilarduya, O., A. E. Moore and I. Kaloshian. 2001. The tomato Rme1 locus is required for Mi-1-mediated resistance to root-knot nematodes and the potato aphid. Plant J. 27:417-425.


More Information

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

Department Information

Department of Nematology
Margarita Flores
1447 Boyce Hall

Tel: (951) 827-3598
Fax: (951) 827-2364